Abatacept-Orencia

Generic Name :: Abatacept

Brand Name :: Orencia

Prescribed For

This medication is a synthetic protein, prescribed for adult rheumatoid arthritis, and juvenile idiopathic arthritis. Abatacept will only be prescribed if patients’s arthritis is active and he/she have tried methotrexate and another disease modifying anti-rheumatic drug (DMARD) such as sulfasalazine or leflunomide.

Preparation::

Powder for Injection: 250 mg. Prefilled Syringe: 125 mg/ml.

Storage:

This medicine should be refrigerated between 2-8 C (36-46 F).

Dosing

· It is usually given in a doctor's office every 2 weeks for the first three doses and then every 4 weeks. It will take about 30 minutes for patients to receive his/her entire dose of abatacept.

Side effects

· Nausea
· Dizziness
· Heartburn
Headache
· Runny nose
· Sore throat

Back pain

· Arm or leg pain
· Hives
· Shortness of breath
· Fever, chills, and other signs of infection
· Dry cough that doesn't go away
· Skin rash
· Itching
· Swelling of the eyes, face, lips, tongue, or throat
· Difficulty breathing or swallowing
Weight loss
Requent urination or sudden need to urinate right away
· Burning during urination
· Cellulitis (red, hot, swollen area on the skin)
Night sweats

About ABATACEPT / ORENCIA

ORENCIA/ABATACEPT is a soluble fusion protein. It consists of the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) linked to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). This medicine is produced by recombinant DNA technology in a mammalian cell expression system. It blocks the activity of T-cells, which causes swelling and joint damage in people with arthritis condition.

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Saturday, 6 October 2012